Cargando…
Functional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells
Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...
Autores principales: | Geißler, Sven, Textor, Martin, Kühnisch, Jirko, Könnig, Delia, Klein, Oliver, Ode, Andrea, Pfitzner, Tilman, Adjaye, James, Kasper, Grit, Duda, Georg N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532360/ https://www.ncbi.nlm.nih.gov/pubmed/23285157 http://dx.doi.org/10.1371/journal.pone.0052700 |
Ejemplares similares
-
Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation
por: Geissler, Sven, et al.
Publicado: (2018) -
In serum veritas—in serum sanitas? Cell non-autonomous aging compromises differentiation and survival of mesenchymal stromal cells via the oxidative stress pathway
por: Geißler, S, et al.
Publicado: (2013) -
Interaction of Age and Mechanical Stability on Bone Defect Healing: An Early Transcriptional Analysis of Fracture Hematoma in Rat
por: Ode, Andrea, et al.
Publicado: (2014) -
Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome
por: Zorn, Malte, et al.
Publicado: (2022) -
Mitochondria-cytoskeleton associations in mammalian cytokinesis
por: Lawrence, E. J., et al.
Publicado: (2016)