Transcriptional Regulation of 15-Lipoxygenase Expression by Histone H3 Lysine 4 Methylation/Demethylation

15-Lipoxygenase-1 (15-LOX-1) oxidizes polyunsaturated fatty acids to a rich spectrum of biologically active metabolites and is implicated in physiological membrane remodelling, inflammation and apoptosis. Its deregulation is involved in the pathogenesis of diverse cancer and immune diseases. Recent...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Xu, Dawei, Han, Hongya, Fan, Yidong, Schain, Frida, Xu, Zhonghua, Claesson, Hans-Erik, Björkholm, Magnus, Sjöberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532411/
https://www.ncbi.nlm.nih.gov/pubmed/23285160
http://dx.doi.org/10.1371/journal.pone.0052703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532411/
https://www.ncbi.nlm.nih.gov/pubmed/23285160
http://dx.doi.org/10.1371/journal.pone.0052703

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