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Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3
SUV39H1, the first identified histone lysine methyltransferase in human, is involved in chromatin modification and gene regulation. SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in methyl-lysine recognition and SUV39H1 targeting. In this study, the structure of th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532415/ https://www.ncbi.nlm.nih.gov/pubmed/23285239 http://dx.doi.org/10.1371/journal.pone.0052977 |