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A Bayesian Model for Pooling Gene Expression Studies That Incorporates Co-Regulation Information

Current Bayesian microarray models that pool multiple studies assume gene expression is independent of other genes. However, in prokaryotic organisms, genes are arranged in units that are co-regulated (called operons). Here, we introduce a new Bayesian model for pooling gene expression studies that...

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Detalles Bibliográficos
Autores principales: Conlon, Erin M., Postier, Bradley L., Methé, Barbara A., Nevin, Kelly P., Lovley, Derek R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532429/
https://www.ncbi.nlm.nih.gov/pubmed/23284902
http://dx.doi.org/10.1371/journal.pone.0052137