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Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin

Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as a t...

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Detalles Bibliográficos
Autores principales: Crumling, Mark A., Liu, Liqian, Thomas, Paul V., Benson, Jennifer, Kanicki, Ariane, Kabara, Lisa, Hälsey, Karin, Dolan, David, Duncan, R. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532434/
https://www.ncbi.nlm.nih.gov/pubmed/23285273
http://dx.doi.org/10.1371/journal.pone.0053280