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Role of Actin Dependent Nuclear Deformation in Regulating Early Gene Expression

The nucleus of a living cell is constantly undergoing changes in shape and size as a result of various mechanical forces in physiology. These changes correlate with alterations in gene expression, however it is unclear whether nuclear deformation alone is sufficient to elicit these alterations. We u...

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Detalles Bibliográficos
Autores principales: Gupta, Soumya, Marcel, Nimi, Sarin, Apurva, Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532443/
https://www.ncbi.nlm.nih.gov/pubmed/23285252
http://dx.doi.org/10.1371/journal.pone.0053031