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Human Sensory Neurons Derived from Induced Pluripotent Stem Cells Support Varicella-Zoster Virus Infection

After primary infection, varicella-zoster virus (VZV) establishes latency in neurons of the dorsal root and trigeminal ganglia. Many questions concerning the mechanism of VZV pathogenesis remain unanswered, due in part to the strict host tropism and inconsistent availability of human tissue obtained...

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Detalles Bibliográficos
Autores principales: Lee, Katherine S., Zhou, Wenbo, Scott-McKean, Jonah J., Emmerling, Kaitlin L., Cai, Guang-yun, Krah, David L., Costa, Alberto C., Freed, Curt R., Levin, Myron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532467/
https://www.ncbi.nlm.nih.gov/pubmed/23285249
http://dx.doi.org/10.1371/journal.pone.0053010