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No Evidence for a Functional Role of Bi-Directional Notch Signaling during Angiogenesis

The Delta-Notch pathway is a signal exchanger between adjacent cells to regulate numerous differentiation steps during embryonic development. Blood vessel formation by sprouting angiogenesis requires high expression of the Notch ligand DLL4 in the leading tip cell, while Notch receptors in the trail...

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Detalles Bibliográficos
Autores principales: Liebler, Sven S., Feldner, Anja, Adam, M. Gordian, Korff, Thomas, Augustin, Hellmut G., Fischer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532505/
https://www.ncbi.nlm.nih.gov/pubmed/23300864
http://dx.doi.org/10.1371/journal.pone.0053074