Local delivery of gene-modifying triplex-forming molecules to epidermis

Epidermal keratinocytes are particularly suitable candidates for in situ gene correction. Intraperitoneal administration of a triplex-forming oligonucleotide (TFO) was shown previously to introduce DNA base changes in a reporter gene in skin, without identifying which cells had been targeted. We ext...

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Detalles Bibliográficos
Autores principales: Rogers, Faye A., Hu, Rong-Hua, Milstone, Leonard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532560/
https://www.ncbi.nlm.nih.gov/pubmed/23014335
http://dx.doi.org/10.1038/jid.2012.351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532560/
https://www.ncbi.nlm.nih.gov/pubmed/23014335
http://dx.doi.org/10.1038/jid.2012.351

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