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Generation and external validation of a tumor-derived 5-gene prognostic signature for recurrence of lymph node-negative, invasive colorectal carcinoma

BACKGROUND: One in 4 patients with lymph node-negative, invasive colorectal carcinoma (CRC) develops recurrent disease after undergoing curative surgery, and most die of advanced disease. Predicting which patients will develop a recurrence is a significantly growing, unmet medical need. METHODS: Arc...

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Detalles Bibliográficos
Autores principales: Lenehan, Peter F, Boardman, Lisa A, Riegert-Johnson, Douglas, De Petris, Giovanni, Fry, David W, Ohrnberger, Jeanne, Heyman, Eugene R, Gerard, Brigitte, Almal, Arpit A, Worzel, William P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532613/
https://www.ncbi.nlm.nih.gov/pubmed/22605513
http://dx.doi.org/10.1002/cncr.27628