Cargando…

Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction

We recently reported the first evidence of placental endoplasmic reticulum (ER) stress in the pathophysiology of human intrauterine growth restriction. Here, we used a mouse model to investigate potential underlying mechanisms. Eif2s1(tm1RjK) mice, in which Ser51 of eukaryotic initiation factor 2 su...

Descripción completa

Detalles Bibliográficos
Autores principales: Yung, Hong wa, Hemberger, Myriam, Watson, Erica D, Senner, Claire E, Jones, Carolyn P, Kaufman, Randal J, Charnock-Jones, D Stephen, Burton, Graham J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532660/
https://www.ncbi.nlm.nih.gov/pubmed/22733590
http://dx.doi.org/10.1002/path.4068