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Stress-induced mutation via DNA breaks in Escherichia coli: A molecular mechanism with implications for evolution and medicine
Evolutionary theory assumed that mutations occur constantly, gradually, and randomly over time. This formulation from the “modern synthesis” of the 1930s was embraced decades before molecular understanding of genes or mutations. Since then, our labs and others have elucidated mutation mechanisms act...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533179/ https://www.ncbi.nlm.nih.gov/pubmed/22911060 http://dx.doi.org/10.1002/bies.201200050 |