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Downregulation of L1 perturbs neuronal migration and alters the expression of transcription factors in murine neocortex

L1 is a cell adhesion molecule associated with a spectrum of human neurological diseases, the most well-known being X-linked hydrocephalus. L1 knockout (L1-KO) mice have revealed a variety of functions of L1 that were crucial in brain development in different brain regions. However; the function of...

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Detalles Bibliográficos
Autores principales: Kishimoto, Tomokazu, Itoh, Kyoko, Umekage, Masafumi, Tonosaki, Madoka, Yaoi, Takeshi, Fukui, Kenji, Lemmon, Vance P, Fushiki, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533181/
https://www.ncbi.nlm.nih.gov/pubmed/23073969
http://dx.doi.org/10.1002/jnr.23141