Cargando…

Regulation of the tumor suppressor PML by sequential post-translational modifications

Post-translational modifications (PTMs) regulate multiple biological functions of the promyelocytic leukemia (PML) protein and also the fission, disassembly, and rebuilding of PML nuclear bodies (PML-NBs) during the cell cycle. Pathway-specific PML modification patterns ensure proper signal output f...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmitz, M. Lienhard, Grishina, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533183/
https://www.ncbi.nlm.nih.gov/pubmed/23293771
http://dx.doi.org/10.3389/fonc.2012.00204