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Isolation of the bioactive peptides CCHamide-1 and CCHamide-2 from Drosophila and their putative role in appetite regulation as ligands for G protein-coupled receptors

There are many orphan G protein-coupled receptors (GPCRs) for which ligands have not yet been identified. One such GPCR is the bombesin receptor subtype 3 (BRS-3). BRS-3 plays a role in the onset of diabetes and obesity. GPCRs in invertebrates are similar to those in vertebrates. Two Drosophila GPCR...

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Detalles Bibliográficos
Autores principales: Ida, Takanori, Takahashi, Tomoko, Tominaga, Hatsumi, Sato, Takahiro, Sano, Hiroko, Kume, Kazuhiko, Ozaki, Mamiko, Hiraguchi, Tetsutaro, Shiotani, Hajime, Terajima, Saki, Nakamura, Yuki, Mori, Kenji, Yoshida, Morikatsu, Kato, Johji, Murakami, Noboru, Miyazato, Mikiya, Kangawa, Kenji, Kojima, Masayasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533232/
https://www.ncbi.nlm.nih.gov/pubmed/23293632
http://dx.doi.org/10.3389/fendo.2012.00177