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Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus

BACKGROUND: The otrC gene of Streptomyces rimosus was previously annotated as an oxytetracycline (OTC) resistance protein. However, the amino acid sequence analysis of OtrC shows that it is a putative ATP-binding cassette (ABC) transporter with multidrug resistance function. To our knowledge, none o...

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Detalles Bibliográficos
Autores principales: Yu, Lan, Yan, Xiangyun, Wang, Long, Chu, Ju, Zhuang, Yingping, Zhang, Siliang, Guo, Meijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533511/
https://www.ncbi.nlm.nih.gov/pubmed/22906146
http://dx.doi.org/10.1186/1472-6750-12-52