Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment

BACKGROUND: Calprotectin consists of the Ca(2+)-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous studies demonstrate their crucial role in pathological con...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiechert, Lars, Németh, Julia, Pusterla, Tobias, Bauer, Christine, De Ponti, Aurora, Manthey, Sandra, Marhenke, Silke, Vogel, Arndt, Klingmüller, Ursula, Hess, Jochen, Angel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533587/
https://www.ncbi.nlm.nih.gov/pubmed/23241281
http://dx.doi.org/10.1186/1478-811X-10-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533587/
https://www.ncbi.nlm.nih.gov/pubmed/23241281
http://dx.doi.org/10.1186/1478-811X-10-40

Ejemplares similares