Pharmacokinetics of an injectable long-acting formulation of doxycycline hyclate in dogs

Based on its PK/PD ratios, doxycycline hyclate (DOX-h), a time-dependant antibacterial, is ideally expected to achieve both sustained plasma drug concentrations at or slightly above the MIC level for as long as possible between dosing intervals. Pursuing this end, a poloxamer-based matrix was used t...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Lilia, Velasco, Zazil-Ha, Vázquez, Carlos, Vargas, Dinorah, Sumano, Héctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533740/
https://www.ncbi.nlm.nih.gov/pubmed/22682068
http://dx.doi.org/10.1186/1751-0147-54-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533740/
https://www.ncbi.nlm.nih.gov/pubmed/22682068
http://dx.doi.org/10.1186/1751-0147-54-35

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