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Identification of Drugs Inducing Phospholipidosis by Novel in vitro Data

Drug-induced phospholipidosis (PLD) is a lysosomal storage disorder characterized by the accumulation of phospholipids within the lysosome. This adverse drug effect can occur in various tissues and is suspected to impact cellular viability. Therefore, it is important to test chemical compounds for t...

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Detalles Bibliográficos
Autores principales: Muehlbacher, Markus, Tripal, Philipp, Roas, Florian, Kornhuber, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533795/
https://www.ncbi.nlm.nih.gov/pubmed/22945602
http://dx.doi.org/10.1002/cmdc.201200306