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Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

Controlling gene expression via small interfering RNA (siRNA) has opened the doors to a plethora of therapeutic possibilities, with many currently in the pipelines of drug development for various ocular diseases. Despite the potential of siRNA technologies, barriers to intracellular delivery signifi...

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Detalles Bibliográficos
Autores principales: Thakur, Ajit, Fitzpatrick, Scott, Zaman, Abeyat, Kugathasan, Kapilan, Muirhead, Ben, Hortelano, Gonzalo, Sheardown, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533807/
https://www.ncbi.nlm.nih.gov/pubmed/22686441
http://dx.doi.org/10.1186/1754-1611-6-7