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Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer

INTRODUCTION: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have become a treatment option in non-small-cell lung cancer (NSCLC) patients. However, despite their use in this disease, a significant number of patients will eventually develop resistance and relapse. In this...

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Detalles Bibliográficos
Autores principales: Murray, Samuel, Karavasilis, Vasilios, Bobos, Mattheos, Razis, Evangelia, Papadopoulos, Savvas, Christodoulou, Christos, Kosmidis, Paris, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533816/
https://www.ncbi.nlm.nih.gov/pubmed/22992338
http://dx.doi.org/10.1186/1756-9966-31-77