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HIV-1 Nef: a multifaceted modulator of T cell receptor signaling
Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is dispensable for viral replication in cell culture, but promotes virus replication and pathogenesis in the infected host. Acting as protein-interaction adaptor, HIV-1 Nef modulates numerous target cell activities includi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534016/ https://www.ncbi.nlm.nih.gov/pubmed/23227982 http://dx.doi.org/10.1186/1478-811X-10-39 |