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SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart

A major component of the cardiac stress response is the simultaneous activation of several gene regulatory networks. Interestingly, the transcriptional regulator steroid receptor coactivator-2, SRC-2 is often decreased during cardiac failure in humans. We postulated that SRC-2 suppression plays a me...

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Detalles Bibliográficos
Autores principales: Reineke, Erin L., York, Brian, Stashi, Erin, Chen, Xian, Tsimelzon, Anna, Xu, Jianming, Newgard, Christopher B., Taffet, George E., Taegtmeyer, Heinrich, Entman, Mark L., O’Malley, Bert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534027/
https://www.ncbi.nlm.nih.gov/pubmed/23300926
http://dx.doi.org/10.1371/journal.pone.0053395