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Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel

Epithelial-mesenchymal transition (EMT) is a crucial event in tumor invasion and metastasis. However, most of past EMT studies have been conducted in the conventional two-dimensional (2D) monolayer culture. Therefore, it remains unclear what invasive phenotypes are acquired by EMT-induced cancer cel...

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Detalles Bibliográficos
Autores principales: Oyanagi, Jun, Ogawa, Takashi, Sato, Hiroki, Higashi, Shouichi, Miyazaki, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534040/
https://www.ncbi.nlm.nih.gov/pubmed/23300891
http://dx.doi.org/10.1371/journal.pone.0053209