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Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel
Epithelial-mesenchymal transition (EMT) is a crucial event in tumor invasion and metastasis. However, most of past EMT studies have been conducted in the conventional two-dimensional (2D) monolayer culture. Therefore, it remains unclear what invasive phenotypes are acquired by EMT-induced cancer cel...
Autores principales: | Oyanagi, Jun, Ogawa, Takashi, Sato, Hiroki, Higashi, Shouichi, Miyazaki, Kaoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534040/ https://www.ncbi.nlm.nih.gov/pubmed/23300891 http://dx.doi.org/10.1371/journal.pone.0053209 |
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