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Simultaneous Single-Sample Determination of NMNAT Isozyme Activities in Mouse Tissues

A novel assay procedure has been developed to allow simultaneous activity discrimination in crude tissue extracts of the three known mammalian nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1) isozymes. These enzymes catalyse the same key reaction for NAD biosynthesis in different...

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Detalles Bibliográficos
Autores principales: Orsomando, Giuseppe, Cialabrini, Lucia, Amici, Adolfo, Mazzola, Francesca, Ruggieri, Silverio, Conforti, Laura, Janeckova, Lucie, Coleman, Michael P., Magni, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534050/
https://www.ncbi.nlm.nih.gov/pubmed/23300904
http://dx.doi.org/10.1371/journal.pone.0053271