Establishment, Characterization and Chemosensitivity of Three Mismatch Repair Deficient Cell Lines from Sporadic and Inherited Colorectal Carcinomas

BACKGROUND: Colorectal cancer (CRC) represents a morphologic and molecular heterogenic disease. This heterogeneity substantially impairs drug effectiveness and prognosis. The subtype of mismatch repair deficient (MMR-D) CRCs, accounting for about 15% of all cases, shows particular differential respo...

Descripción completa

Detalles Bibliográficos
Autores principales: Maletzki, Claudia, Stier, Saskia, Gruenert, Ulrike, Gock, Michael, Ostwald, Christiane, Prall, Friedrich, Linnebacher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534085/
https://www.ncbi.nlm.nih.gov/pubmed/23300683
http://dx.doi.org/10.1371/journal.pone.0052485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534085/
https://www.ncbi.nlm.nih.gov/pubmed/23300683
http://dx.doi.org/10.1371/journal.pone.0052485

Ejemplares similares