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Establishment, Characterization and Chemosensitivity of Three Mismatch Repair Deficient Cell Lines from Sporadic and Inherited Colorectal Carcinomas
BACKGROUND: Colorectal cancer (CRC) represents a morphologic and molecular heterogenic disease. This heterogeneity substantially impairs drug effectiveness and prognosis. The subtype of mismatch repair deficient (MMR-D) CRCs, accounting for about 15% of all cases, shows particular differential respo...
Autores principales: | Maletzki, Claudia, Stier, Saskia, Gruenert, Ulrike, Gock, Michael, Ostwald, Christiane, Prall, Friedrich, Linnebacher, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534085/ https://www.ncbi.nlm.nih.gov/pubmed/23300683 http://dx.doi.org/10.1371/journal.pone.0052485 |
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