EZH2 Promotes Malignant Behaviors via Cell Cycle Dysregulation and Its mRNA Level Associates with Prognosis of Patient with Non-Small Cell Lung Cancer

BACKGROUND: Epigenetic silencing is a common mechanism to inactivate tumor suppressor genes during carcinogenesis. Enhancer of Zeste 2 (EZH2) is the histone methyltransferase subunit in polycomb repressive complex 2 which mediates transcriptional repression through histone methylation. EZH2 overexpr...

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Detalles Bibliográficos
Autores principales: Cao, Wei, Ribeiro, Rachel de Oliveira, Liu, Diane, Saintigny, Pierre, Xia, Ronghui, Xue, Yuwen, Lin, Ruxian, Mao, Li, Ren, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534094/
https://www.ncbi.nlm.nih.gov/pubmed/23300840
http://dx.doi.org/10.1371/journal.pone.0052984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534094/
https://www.ncbi.nlm.nih.gov/pubmed/23300840
http://dx.doi.org/10.1371/journal.pone.0052984

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