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Dynamic Regulation of Phenylalanine Hydroxylase by Simulated Redox Manipulation

Recent clinical studies revealed increased phenylalanine levels and phenylalanine to tyrosine ratios in patients suffering from infection, inflammation and general immune activity. These data implicated down-regulation of activity of phenylalanine hydroxylase by oxidative stress upon in vivo immune...

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Detalles Bibliográficos
Autores principales: Fuchs, Julian E., Huber, Roland G., von Grafenstein, Susanne, Wallnoefer, Hannes G., Spitzer, Gudrun M., Fuchs, Dietmar, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534100/
https://www.ncbi.nlm.nih.gov/pubmed/23300845
http://dx.doi.org/10.1371/journal.pone.0053005