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Dynamic Regulation of Phenylalanine Hydroxylase by Simulated Redox Manipulation
Recent clinical studies revealed increased phenylalanine levels and phenylalanine to tyrosine ratios in patients suffering from infection, inflammation and general immune activity. These data implicated down-regulation of activity of phenylalanine hydroxylase by oxidative stress upon in vivo immune...
Autores principales: | Fuchs, Julian E., Huber, Roland G., von Grafenstein, Susanne, Wallnoefer, Hannes G., Spitzer, Gudrun M., Fuchs, Dietmar, Liedl, Klaus R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534100/ https://www.ncbi.nlm.nih.gov/pubmed/23300845 http://dx.doi.org/10.1371/journal.pone.0053005 |
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