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Functional DNA Repair Signature of Cancer Cell Lines Exposed to a Set of Cytotoxic Anticancer Drugs Using a Multiplexed Enzymatic Repair Assay on Biochip

The development of resistances to conventional anticancer drugs compromises the efficacy of cancer treatments. In the case of DNA-targeting chemotherapeutic agents, cancer cells may display tolerance to the drug-induced DNA lesions and/or enhanced DNA repair. However, the role of DNA damage response...

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Detalles Bibliográficos
Autores principales: Forestier, Anne, Sarrazy, Fanny, Caillat, Sylvain, Vandenbrouck, Yves, Sauvaigo, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534104/
https://www.ncbi.nlm.nih.gov/pubmed/23300565
http://dx.doi.org/10.1371/journal.pone.0051754