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Cardiomyocyte-Specific Overexpression of HEXIM1 Prevents Right Ventricular Hypertrophy in Hypoxia-Induced Pulmonary Hypertension in Mice

Right ventricular hypertrophy (RVH) and right ventricular (RV) contractile dysfunction are major determinants of prognosis in pulmonary arterial hypertension (PAH) and PAH remains a severe disease. Recently, direct interruption of left ventricular hypertrophy has been suggested to decrease the risk...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Noritada, Shimizu, Noriaki, Maruyama, Takako, Sano, Motoaki, Matsuhashi, Tomohiro, Fukuda, Keiichi, Kataoka, Masaharu, Satoh, Toru, Ojima, Hidenori, Sawai, Takashi, Morimoto, Chikao, Kuribara, Akiko, Hosono, Osamu, Tanaka, Hirotoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534105/
https://www.ncbi.nlm.nih.gov/pubmed/23300697
http://dx.doi.org/10.1371/journal.pone.0052522