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Fine Mapping of a Region of Chromosome 11q23.3 Reveals Independent Locus Associated with Risk of Glioma

BACKGROUND: A single nucleotide polymorphism (SNP) at locus 11q23.3 (rs498872) in the near 5′-UTR of the PHLDB1 gene was recently implicated as a risk factor for gliomas in a genome-wide association study, and this involvement was confirmed in three additional studies. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalles Bibliográficos
Autores principales: Chen, Hongyan, Sun, Bing, Zhao, Yingjie, Song, Xiao, Fan, Weiwei, Zhou, Keke, Zhou, Liangfu, Mao, Ying, Lu, Daru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534108/
https://www.ncbi.nlm.nih.gov/pubmed/23300798
http://dx.doi.org/10.1371/journal.pone.0052864