p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions

α-Synuclein is the main component of Lewy bodies, the intraneuronal inclusion bodies characteristic of Parkinson’s disease. Although α-synuclein accumulation is caused by inhibition of proteasome and autophagy-lysosome, the degradation of α-synuclein inclusions is still unknown. Formation of Lewy bo...

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Detalles Bibliográficos
Autores principales: Watanabe, Yoshihisa, Tatebe, Harutsugu, Taguchi, Katsutoshi, Endo, Yasuhisa, Tokuda, Takahiko, Mizuno, Toshiki, Nakagawa, Masanori, Tanaka, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534125/
https://www.ncbi.nlm.nih.gov/pubmed/23300799
http://dx.doi.org/10.1371/journal.pone.0052868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534125/
https://www.ncbi.nlm.nih.gov/pubmed/23300799
http://dx.doi.org/10.1371/journal.pone.0052868

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