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CCR2 overexpression promotes the efficient recruitment of retinal microglia in vitro

PURPOSE: Retinal microglia can be activated and recruited by chemokines and play a protective role in early retinal degeneration. CC-chemokine ligand 2 (CCL2) and its receptor, CC-chemokine receptor 2 (CCR2), have been implicated as key mediators for the trafficking and accumulation of microglial ce...

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Detalles Bibliográficos
Autores principales: Jiang, Xiao-shuang, Ni, Ying-qin, Liu, Tian-jin, Zhang, Meng, Ren, Hui, Jiang, Rui, Huang, Xin, Xu, Ge-zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534147/
https://www.ncbi.nlm.nih.gov/pubmed/23288990