Microtubule S-glutathionylation as a potential approach for antimitotic agents

BACKGROUND: Microtubules have been one of the most effective targets for the development of anticancer agents. Cancer cells treated by these agents are characterized by cell arrest at G(2)/M phase. Microtubule-targeting drugs are, therefore, referred to as antimitotic agents. However, the clinical a...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Seefeldt, Teresa, Young, Alan, Zhang, Xiaoying, Zhao, Yong, Ruffolo, John, Kaushik, Radhey S, Guan, Xiangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534152/
https://www.ncbi.nlm.nih.gov/pubmed/22703118
http://dx.doi.org/10.1186/1471-2407-12-245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534152/
https://www.ncbi.nlm.nih.gov/pubmed/22703118
http://dx.doi.org/10.1186/1471-2407-12-245

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