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Tumor vessel-injuring ability improves antitumor effect of cytotoxic T lymphocytes in adoptive immunotherapy

Angiogenesis is required for normal physiologic processes, but it is also involved in tumor growth, progression and metastasis. Here, we report the development of an immune-based antiangiogenic strategy based on the generation of T lymphocytes that possess killing specificity for cells expressing va...

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Detalles Bibliográficos
Autores principales: Kanagawa, N, Yanagawa, T, Nakagawa, T, Okada, N, Nakagawa, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534155/
https://www.ncbi.nlm.nih.gov/pubmed/23175243
http://dx.doi.org/10.1038/cgt.2012.85