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Airway CD8(+) T cells induced by pulmonary DNA immunization mediate protective anti-viral immunity
Vaccination strategies for protection against a number of respiratory pathogens must induce T-cell populations in both the pulmonary airways and peripheral lymphoid organs. In this study, we show that pulmonary immunization using plasmid DNA formulated with the polymer polyethyleneimine (PEI-DNA) in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534169/ https://www.ncbi.nlm.nih.gov/pubmed/22806099 http://dx.doi.org/10.1038/mi.2012.59 |