Dual Inhibition of Plasminogen Kringle 5 on Angiogenesis and Chemotaxis Suppresses Tumor Metastasis by Targeting HIF-1α Pathway

We had demonstrated that plasminogen kringle 5 (K5), a potent angiogenic inhibitor, inhibited retinal neovascularization and hepatocellular carcinoma growth by anti-angiogenesis. The current study investigated the effects and the underlying mechanisms of K5 on both tumor growth and spontaneous pulmo...

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Detalles Bibliográficos
Autores principales: Cai, Wei-Bin, Zhang, Yang, Cheng, Rui, Wang, Zheng, Fang, Shu-Huan, Xu, Zu-Min, Yang, Xia, Yang, Zhong-Han, Ma, Jian-Xing, Shao, Chun-Kui, Gao, Guo-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534244/
https://www.ncbi.nlm.nih.gov/pubmed/23300882
http://dx.doi.org/10.1371/journal.pone.0053152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534244/
https://www.ncbi.nlm.nih.gov/pubmed/23300882
http://dx.doi.org/10.1371/journal.pone.0053152

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