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Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime
The heritability of most common, multifactorial diseases is rather modest and known genetic effects account for a small part of it. The remaining portion of disease aetiology has been conventionally ascribed to environmental effects, with an unknown part being stochastic. This review focuses on rece...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534255/ https://www.ncbi.nlm.nih.gov/pubmed/23172682 http://dx.doi.org/10.1136/jmedgenet-2012-101322 |