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Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime

The heritability of most common, multifactorial diseases is rather modest and known genetic effects account for a small part of it. The remaining portion of disease aetiology has been conventionally ascribed to environmental effects, with an unknown part being stochastic. This review focuses on rece...

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Detalles Bibliográficos
Autores principales: Forsberg, Lars Anders, Absher, Devin, Dumanski, Jan Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534255/
https://www.ncbi.nlm.nih.gov/pubmed/23172682
http://dx.doi.org/10.1136/jmedgenet-2012-101322

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