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4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

The cell envelope of Mycobacterium tuberculosis, the causative agent of tuberculosis in humans, contains lipids with unusual structures. These lipids play a key role in both virulence and resistance to the various hostile environments encountered by the bacteria during infection. They are synthesize...

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Detalles Bibliográficos
Autores principales: Leblanc, Cécile, Prudhomme, Thomas, Tabouret, Guillaume, Ray, Aurélie, Burbaud, Sophie, Cabantous, Stéphanie, Mourey, Lionel, Guilhot, Christophe, Chalut, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534377/
https://www.ncbi.nlm.nih.gov/pubmed/23308068
http://dx.doi.org/10.1371/journal.ppat.1003097