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The utility of comparative models and the local model quality for protein crystal structure determination by Molecular Replacement

BACKGROUND: Computational models of protein structures were proved to be useful as search models in Molecular Replacement (MR), a common method to solve the phase problem faced by macromolecular crystallography. The success of MR depends on the accuracy of a search model. Unfortunately, this paramet...

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Detalles Bibliográficos
Autores principales: Pawlowski, Marcin, Bujnicki, Janusz M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534383/
https://www.ncbi.nlm.nih.gov/pubmed/23126528
http://dx.doi.org/10.1186/1471-2105-13-289