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Improved base-calling and quality scores for 454 sequencing based on a Hurdle Poisson model
BACKGROUND: 454 pyrosequencing is a commonly used massively parallel DNA sequencing technology with a wide variety of application fields such as epigenetics, metagenomics and transcriptomics. A well-known problem of this platform is its sensitivity to base-calling insertion and deletion errors, part...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534400/ https://www.ncbi.nlm.nih.gov/pubmed/23151247 http://dx.doi.org/10.1186/1471-2105-13-303 |