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Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray

BACKGROUND: The noninvasive prenatal diagnosis procedures that are currently used to detect genetic diseases do not achieve desirable levels of sensitivity and specificity. Recently, fetal methylated DNA biomarkers in maternal peripheral blood have been explored for the noninvasive prenatal detectio...

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Detalles Bibliográficos
Autores principales: Yin, Aihua, Zhang, Xiangzhong, Wu, Jing, Du, Li, He, Tianwen, Zhang, Xiaozhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534415/
https://www.ncbi.nlm.nih.gov/pubmed/22709530
http://dx.doi.org/10.1186/1755-8794-5-26