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Screening significantly hypermethylated genes in fetal tissues compared with maternal blood using a methylated-CpG island recovery assay-based microarray
BACKGROUND: The noninvasive prenatal diagnosis procedures that are currently used to detect genetic diseases do not achieve desirable levels of sensitivity and specificity. Recently, fetal methylated DNA biomarkers in maternal peripheral blood have been explored for the noninvasive prenatal detectio...
Autores principales: | Yin, Aihua, Zhang, Xiangzhong, Wu, Jing, Du, Li, He, Tianwen, Zhang, Xiaozhuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534415/ https://www.ncbi.nlm.nih.gov/pubmed/22709530 http://dx.doi.org/10.1186/1755-8794-5-26 |
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