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Scalable production of biliverdin IXα by Escherichia coli

BACKGROUND: Biliverdin IXα is produced when heme undergoes reductive ring cleavage at the α-methene bridge catalyzed by heme oxygenase. It is subsequently reduced by biliverdin reductase to bilirubin IXα which is a potent endogenous antioxidant. Biliverdin IXα, through interaction with biliverdin re...

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Detalles Bibliográficos
Autores principales: Chen, Dong, Brown, Jason D, Kawasaki, Yukie, Bommer, Jerry, Takemoto, Jon Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534565/
https://www.ncbi.nlm.nih.gov/pubmed/23176158
http://dx.doi.org/10.1186/1472-6750-12-89