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Scalable production of biliverdin IXα by Escherichia coli
BACKGROUND: Biliverdin IXα is produced when heme undergoes reductive ring cleavage at the α-methene bridge catalyzed by heme oxygenase. It is subsequently reduced by biliverdin reductase to bilirubin IXα which is a potent endogenous antioxidant. Biliverdin IXα, through interaction with biliverdin re...
Autores principales: | Chen, Dong, Brown, Jason D, Kawasaki, Yukie, Bommer, Jerry, Takemoto, Jon Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534565/ https://www.ncbi.nlm.nih.gov/pubmed/23176158 http://dx.doi.org/10.1186/1472-6750-12-89 |
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