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p38β MAPK upregulates atrogin1/MAFbx by specific phosphorylation of C/EBPβ
BACKGROUND: The p38 mitogen-activated protein kinases (MAPK) family plays pivotal roles in skeletal muscle metabolism. Recent evidence revealed that p38α and p38β exert paradoxical effects on muscle protein homeostasis. However, it is unknown why p38β, but not p38α, is capable of mediating muscle ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534568/ https://www.ncbi.nlm.nih.gov/pubmed/23046544 http://dx.doi.org/10.1186/2044-5040-2-20 |